Xueli Zhang

Research Assistant Professor

Department of Microbiology and Cell Science

Post-doc, Department of Microbiology and Cell Science, University of Florida
Ph.D., 2005, Shanghai Jiao Tong University, China
B.S., 2000, Shanghai Jiao Tong University, China

Research Interest

Metabolic engineering of bacteria to produce renewable fuels and chemicals.     
1. Engineering E. coli and Klebsiella oxytoca strains for ethanol production from cellulosic hydrolysate.
2. Engineering E. coli strains for bicarboxylic acids and derivatives production (succinate, malate, and aspartate)
3. Engineering E. coli strains for converting glycerol to ethanol and succinate
4. Engineering E. coli strains for L-alanine production

Selected Publications

1. Zhang X, Jantama K, Shanmugam KT, Ingram LO. Phosphoenolpyruvate carboxykinase: an energy-efficient pathway for fermentative cell growth and succinate production in E. coli. In preparation.

2. Jantama K, Haupt MJ, Svoronos SA, Zhang X, Moore JC, Shanmugam KT, Ingram LO. Combining metabolic engineering and metabolic evolution to develop nonrecombinant strains of E. coli C that produce succinate and malate. Biotech Bioeng. In press.

3. Zhang X, Jantama K, Moore JC, Shanmugam KT, Ingram LO. Production of L:-alanine by metabolically engineered Escherichia coli. Appl Microbiol Biotech. 2007, 77(2): 355-366.

4. Zhang X, Yan X, Gao P, Wang L, Zhou Z, Zhao L. Optimized sequence retrieval from single bands of TGGE (temperature gradient gel electrophoresis) profiles of the amplified 16S rDNA fragments from an activated sludge system. J Microbiol Methods. 2005, 60(1): 1-11.

5. Zhang X, Gao P, Chao Q, Wang L, Senior E, Zhao L. Microdiversity of phenol hydroxylase genes among phenol-degrading isolates of Alcaligenes sp. from an activated sludge system. FEMS Microbiol Lett. 2004, 237(2): 369-375.

Patents

1. Jantama K, Haupt MJ, Zhang X, Moore JC, Shanmugam KT, Ingram LO. Materials and methods for efficient succinate and malate production. US Patent Serial No. 60/895,806

2. Zhang X, Jantama K, Moore JC, Shanmugam KT, Ingram LO. Materials and methods for efficient alanine production. US Patent Serial No. 60/908,234

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